The REU Science Communication Workshop was developed by Carol Lynn Alpert and the Strategic Projects Group at the Museum of Science, Boston, in collaboration with the Center for High-rate Nanomanufacturing NSF NSEC at Northeastern University, the University of Massachusetts-Lowell, and the University of New Hampshire, and the “Nanoscale Systems and Their Device Applications” NSF NSEC at Harvard University. The University of Massachusetts Donahue Institute provided professional research and evaluation services. Funding was provided by the National Science Foundation and the Massachusetts Technology Collaborative through NSEC sub-awards. This guide was prepared with the assistance of Karine Thate and Jeanne Antill at the Museum of Science. The dissemination version of this professional development program was developed in collaboration with Andrew Greenberg and the Institute for Chemical Education at the University of Wisconsin-Madison, with support from the National Science Foundation through the NISE Network under award 0940143. Any opinions, findings, and conclusions or recommendations are those of the author(s) and do not necessarily reflect the views of the Foundation.